BRCA1 EXPRESSION IS AN IMPORTANT BIOMARKER FOR CHEMOSENSITIVITY: SUPPRESSION OF BRCA1 INCREASES THE APOPTOSIS VIA UP-REGULATION OF P53 AND P21 DURING CISPLATIN TREATMENT IN OVARIAN CANCER CELLS

BRCA1 is a tumor suppressor which plays a crucial role in the repair of DNA double-strand breaks, Screens and its abnormality is responsible for hereditary ovarian cancer syndrome.It has recently been reported that reduced expression of BRCA1 is also common in sporadic ovarian carcinoma via its promoter hypermethylation, and that ovarian carcinoma

AbstractThe paper investigates the relationship between voting power of political party in local parliament and auditor opinion of local government financial statement.Using a 2009 dataset consisting of 383 local government financial statements, the paper borrows agency framework to advancing a testable hypotheses predicting that voting Screens pow

Leaves are the most abundant and visible Screens plant organ, both in the modern world and the fossil record.Identifying foliage to the correct plant family based on leaf architecture is a fundamental botanical skill that is also critical for isolated fossil leaves, which often, especially in the Cenozoic, represent extinct genera and species from

The One Hitters studied farms are small family businesses, and so, in more than half of the cases, their continuity is not guaranteed.Livestock management is typical of a mountain system, in which the animals graze throughout the year in cultivated fields, sown meadows, forests near the farms, and mountain pastures during the three summer months.Th